Southwest Virginia & Stokes County, NC
| Male Isaac Winfrey "Doc" Holbrook Jr. |
| Birth | Jan 1841 | Tazewell County, Virginia  |
| Death | 10 Feb 1922 | Richmond, Henrico, Virginia |
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| Female Cosbi Jane Brewster |
| Birth | 09 Feb 1840 | Tazewell County, Virginia |
| Death | 30 Jan 1902 | Webster County, West Virginia |
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| Female Rebecca Layuna Holbrook |
| Birth | 30 Sep 1867 | McDowell County, West Virginia |
| Death | 19 Aug 1884 | Birch River, Webster, West Virginia |
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| Spouse | Fleming "Flem" Pack | F894 | |
| Marriage | 15 Jul 1884 | McDowell County, West Virginia |
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